Epimedium extract, derived from the traditional Chinese herb known as "horny goat weed," is increasingly recognized for its significant therapeutic potential beyond its historical use. Modern research has identified its primary bioactive compound, icariin, as a key driver of its benefits. Studies demonstrate its efficacy in supporting bone health by promoting osteoblast activity, making it a promising candidate for managing osteoporosis. Furthermore, its neuroprotective properties are being investigated for cognitive support, while its anti-inflammatory and antioxidant effects show promise for cardiovascular wellness. This positions Epimedium extract as a compelling, multi-target botanical for integrative health strategies, bridging ancient wisdom with contemporary scientific validation.